- Thalassemia - https://www.thalassemia.ca -

Past Research Grant Recipients

Gary Sweeney, York University
Investigation of the influence of gut microbiota and metabolites on complications of thalassemia

Juergen Ehlting, University of Victoria
Plant Secondary Metabolites (phytochemicals) in Iron Overload Treatment

Douglas Templeton, University of Toronto
Chronic iron chelation and susceptibility to toxic metals in the environment

Konstantinos Pantopoulos, Lady Davis Institute
Iron chelation properties of nanoparticle-encapsulated deferoxamine in cells and mice

2014 – 2015
Ali Amid, Hospital for Sick Children
Perception of Thalassemia Patients towards Thalassemia Prenatal Diagnosis Programs; An International Multicenter Study

2013 – 2015
Maria Giovanna Trivieri, University Health Network
The use of the Calcium Channel Blocker Amlodipine as anadjuvant treatment to iron chelation for the prevention of Iron Overload Cardiomyopathy

2011 – 2013
Farzana Sayani, University of Calgary
Detection of F2-isoprostanes as markers of iron-associated oxidative damage and the resulting effects of metabolic systems in iron overloaded beta-thalassemia major patients.

2010 – 2012
Peter Pawelek, Concordia University
Structural Characterization of the Ferrioxamine B Receptor of Vibrio vulnificus, an Opportunistic Pathogen Associated with Thalassemia.

Nancy Olivieri, Toronto General Hospital
Factors affecting the frequency and severity of atrial fibrillation in population at high risk of developing cardiac complications.

2008 – 2010
Jadwiga Gasiorek, Lady Davis Institute for Medical Research
Analysis of novel regulators of erythroid differentiation
(in partnership with CIHR)

Chandra Chaturvedi, Ottawa Hospital Research Institute
Role of G9a in regulating ß-globin gene transcription.
(in partnership with CIHR)

2008 – 2009
Volker Blank, McGill University
Novel regulators of red blood cell differentiation

Douglas Templeton, University of Toronto
Renal Tubular Transport of Iron Chelates

2005 – 2007
Volker Blank, McGill University
Role of Heme and NF-E2 in Balanced Globin Gene Expression

2003 – 2005
John Lafferty; David Barth, St. Joseph’s Hospital
A Multicentre Study of the Effectiveness of the Alpha – Globin Enzyme Linked Immunosorbent Assay (ELISA) as a Screening Technique for Alpha Thalassemia

Prior to 2003

Prem Ponka, Lady Davis Institute for Medical Research; Joan Buss, McGill University
Intraerythrocytic Iron Chelation Diminishes Oxidative Damage in Alpha–Thalassemic Erythrocytes

David Picketts; Natalie Berube, Ottawa Hospital Research Institute
Functional Analysis of ATR-X, the Gene Mutated in Alpha Thalassemia/Mental Syndrome

Douglas Templeton; Ying Liu, University of Toronto

James Ellis, Hospital for Sick Children; Cameron Osborne, University of Toronto
Development of Retroviral Vectors for Gene Therapy of ß-Thalassemia

Melanie Kirby, Toronto General Hospital; Supriya Sharma, University of Toronto
Randomized Trial of Injections and Infusions of Deferoxamine